Restoring Minds, Rebuilding Lives: Our Commitment to Traumatic Brain Injury
Contact us to learn more about our clinical trial in TBI
About Us
Welcome to Abalonex, a pharmaceutical company dedicated to investigating innovative treatments for traumatic brain injury (TBI). We are conducting a Phase 2a clinical trial for ABX-101, a promising therapeutic with potential to target cerebral edemas commonly found in TBI patients.
Traumatic Brain Injury
Traumatic brain injury is a serious condition that affects millions of people globally each year. It is typically caused by blunt force trauma to the head, resulting in damage to the brain that can cause a range of physical, cognitive, and emotional symptoms. TBI can have a profound impact on people's lives, often leading to long-term disabilities, impaired cognitive function, and emotional disturbances.
At Abalonex, we are committed to developing effective treatments for TBI that can improve the lives of those affected by this condition. Our team of experienced scientists and medical professionals are working tirelessly to advance the development of ABX-101, a medication that has shown promise in addressing some of the most common symptoms of TBI.
ABX-101
ABX-101, a known CaM inhibitor, may be a viable option in moderate to severe TBI patients, improving recovery post-CNS injuries. Studies have shown that calmodulin inhibition using ABX-101 has inhibited AQP4 localization to the blood-spinal cord barrier, ablated CNS edema, and led to accelerated functional recovery in rats. Inhibiting AQP4-mediated cerebral edema by targeting CaM with ABX-101 may therefore provide some therapeutic benefits for trauma- and stroke-associated cerebral edema during the acute phase.
Pipeline
ABX-101
Preclinical
Phase 1
Phase 2
Phase 2a
Phase 3
Our clinical trial for ABX-101 is designed to rigorously test the safety and efficacy of this medication in moderate-to-severe TBI patients, with the goal to provide patients an effective treatment to mitigate symptoms caused from TBI. We believe that our work has the potential to make a difference in the lives of TBI patients and their families, and we are dedicated to pursuing this mission with passion and dedication.